Localized gastric distension disrupts slow-wave entrainment leading to temporary ectopic propagation: a high-resolution electrical mapping study-Reference-Cited by-同舟云学术

Localized gastric distension disrupts slow-wave entrainment leading to temporary ectopic propagation: a high-resolution electrical mapping study

Published:2021-12-01 Issue:6 Volume:321 Page:G656-G667
ISSN:0193-1857
Container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology
language:en
Short-container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology

Author:

Chan Chih-Hsiang Alexander¹^ORCID,Aghababaie Zahra¹,Paskaranandavadivel Niranchan¹²^ORCID,Avci Recep¹^ORCID,Cheng Leo K.¹³,Angeli-Gordon Timothy R.¹²^ORCID

Affiliation:

1. Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand

2. Department of Surgery, University of Auckland, Auckland, New Zealand

3. Department of Surgery, Vanderbilt University, Nashville, Tennessee

Abstract

This study presents the discovery of temporary dysrhythmic ectopic pacemakers in the distal stomach caused by localized gastric distension. Distension-induced dysrhythmias are an interesting physiological phenomenon that can inform the design of new interventional and electrophysiological protocols for both research and the clinic. The observation of distension-induced dysrhythmias also contributes to our understanding of stretch-sensitivity in the gut and may play an important role in normal and abnormal postprandial physiology.

Funder

Manatu Hauora | Health Research Council of New Zealand

MedTech CoRE

Royal Society of New Zealand

Publisher

American Physiological Society

Subject

Physiology (medical),Gastroenterology,Hepatology,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpgi.00219.2021

Reference55 articles.

1. Gut peristalsis is governed by a multitude of cooperating mechanisms