Biomarkers for assessment of intestinal permeability in clinical practice-Reference-Cited by-同舟云学术

Biomarkers for assessment of intestinal permeability in clinical practice

Published:2021-07-01 Issue:1 Volume:321 Page:G11-G17
ISSN:0193-1857
Container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology
language:en
Short-container-title:American Journal of Physiology-Gastrointestinal and Liver Physiology

Author:

Seethaler Benjamin¹,Basrai Maryam¹,Neyrinck Audrey M.²,Nazare Julie-Anne³,Walter Jens⁴,Delzenne Nathalie M.²,Bischoff Stephan C.¹

Affiliation:

1. Institute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany

2. Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique de Louvain (UCLouvain), Brussels, Belgium

3. Human Nutrition Research Center Rhône-Alpes (CRNH Rhône-Alpes), CarMeN Laboratory, Univ-Lyon, Université Claude Bernard Lyon1, Lyon, France

4. APC Microbiome Ireland, School of Microbiology and Department of Medicine, University College Cork - National University of Ireland Cork, Cork, Ireland

Abstract

This study shows that biomarkers from blood and fecal samples are associated with the cumbersome established tests of intestinal permeability throughout different cohorts. Therefore, such biomarkers could be used to assess gut barrier function in prospective cohort studies and large-scale clinical trials for which tracer-based tests may not be feasible.

Funder

Bundesministerium für Bildung und Forschung

Publisher

American Physiological Society

Subject

Physiology (medical),Gastroenterology,Hepatology,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpgi.00113.2021

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