Fetal alcohol exposure reduces responsiveness of taste nerves and trigeminal chemosensory neurons to ethanol and its flavor components-Reference-Cited by-同舟云学术

Fetal alcohol exposure reduces responsiveness of taste nerves and trigeminal chemosensory neurons to ethanol and its flavor components

Published:2017-08-01 Issue:2 Volume:118 Page:1198-1209
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

Glendinning John I.¹²,Tang Joyce¹,Morales Allende Ana Paula¹,Bryant Bruce P.³,Youngentob Lisa⁴²,Youngentob Steven L.⁴²

Affiliation:

1. Barnard College, Columbia University, New York, New York

2. SUNY Developmental Exposure Alcohol Research Center, Binghamton, New York

3. Monell Chemical Senses Center, Philadelphia, Pennsylvania

4. University of Tennessee Health Science Center, Memphis, Tennessee

Abstract

Pregnant mothers are advised to avoid alcohol. This is because even small amounts of alcohol can alter fetal brain development and increase the risk of adolescent alcohol abuse. We asked how fetal alcohol exposure (FAE) produces the latter effect in adolescent rats by measuring responsiveness of taste nerves and trigeminal chemosensory neurons. We found that FAE substantially reduced taste and trigeminal responsiveness to ethanol and its flavor components.

Funder

HHS | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAA)

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

Link

https://www.physiology.org/doi/pdf/10.1152/jn.00108.2017

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