Measurement of myocardial blood flow using krypton 85

Author:

Cohen Lawrence S.1,Elliott William C.1,Gorlin Richard1

Affiliation:

1. Medical Clinics, Peter Bent Brigham Hospital and Harvard Medical School, Boston, Massachusetts

Abstract

Krypton 85 in solution was administered as a single rapid injection into the left ventricle in 11 human and 9 canine subjects. The myocardial clearance of the portion of injectate which entered the coronary system was sampled at the coronary sinus and coronary flow was derived from Kety's equation. A comparison with nitrous oxide or antipyrine-I131 coronary flows revealed a correlation coefficient of 0.86 ± 0.22 ( P = .005) with no statistically significant difference between paired samples.

Publisher

American Physiological Society

Subject

Physiology (medical)

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