Diodrast (I131) whole blood clearance as an index of renal blood flow

Author:

Fozzard Harry A.1

Affiliation:

1. Naval Medical Field Research Laboratory, Camp Lejeune, North Carolina

Abstract

The whole blood clearance of Diodrast (I131) following a single intravenous injection was used to estimate renal blood flow. This method was compared to renal blood flow simultaneously determined by the PAH constant infusion technique. A correlation coefficient of 0.930 was found. The Diodrast clearance method is recommended because it is simple and rapid, and it avoids the necessity for urine collection.

Publisher

American Physiological Society

Subject

Physiology (medical)

Cited by 20 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Clearance Techniques;Comprehensive Physiology;1992-12

2. Physiologically based pharmacokinetic model for the renal clearance of iodopyracet and the interaction with probenecid in the dog;Biopharmaceutics & Drug Disposition;1989-03

3. Renal radiopharmaceuticals—An update;Seminars in Nuclear Medicine;1982-07

4. Kinetic modeling of the renal excretion of iodopyracet in the dog;Journal of Pharmacokinetics and Biopharmaceutics;1982-02

5. Radionuclides in Urology;Diagnostic Radiology;1977

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