Excretion of Radioactive Zinc (Zn65) in Bile, Pancreatic and Duodenal Secretions of the Dog

Abstract

There is more Zn65 secreted per cubic centimeter of sample, and per volume collected in pure pancreatic juice than in bile or duodenal secretions. The increased radioactivity of pancreatic juice appears earlier, reaches a higher peak, and lasts longer than corresponding collections of bile or duodenal juice as periodically measured during the first 6 hours following intravenous injection of radioactive zinc (Zn65). Ligation of the pancreatic ducts materially decreases the radioactivity of otherwise intact duodenal aspirate.