Histidine decarboxylase-mediated histamine synthesis in glomeruli from rat kidneys

Author:

Heald JI,Hollis TM

Abstract

Enzymatic histamine synthesis by renal glomeruli of the rat has been examined. Assays of the partially purified enzyme demonstrated a pH optimum of 6.2, a Michaelis-Menten constant of 2.4 X 10(-4) histidine, and lack of potentiation by benzene. These data thus indicate that renal glomeruli contain the histidine-specific histidine decarboxylase.

Publisher

American Physiological Society

Subject

Physiology (medical)

Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Histamine in the kidneys: what is its role in renal pathophysiology?;British Journal of Pharmacology;2019-04-15

2. The effect of histamine on kidney by fasting in rats;Bratislava Medical Journal;2013

3. Inhibition of post-ischemic reperfusion injury of the kidney by diamine oxidase;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;1998-09

4. Formation of Histamine: Histidine Decarboxylase;Histamine and Histamine Antagonists;1991

5. [8] Preparation and study of isolated glomeruli;Methods in Enzymology;1990

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