Pulmonary venular responses to anoxia, 5-hydroxytryptamine and histamine-Reference-Cited by-同舟云学术

Pulmonary venular responses to anoxia, 5-hydroxytryptamine and histamine

Published:1960-05-01 Issue:5 Volume:198 Page:1032-1036
ISSN:0002-9513
Container-title:American Journal of Physiology-Legacy Content
language:en
Short-container-title:American Journal of Physiology-Legacy Content

Author:

Aviado Domingo M.¹

Affiliation:

1. Laboratory of Pharmacology, University of Pennsylvania Schools of Medicine, Philadelphia, Pennsylvania

Abstract

In anesthetized dogs, the inhalation of 5% oxygen causes a rise in pulmonary arterial pressure but no rise in venular pressures measured by catheters with outside diameters of 0.4 mm and 1.0 mm. The venular pressure measured by the 0.4-mm catheter showed a consistent rise to 5-hydroxytryptamine. This venular constrictor response to 5-hydroxytryptamine is encountered even when pulmonary blood flow is kept constant by perfusion. The venular response to histamine is variable.

Publisher

American Physiological Society

Subject

Physiology (medical)

Link

https://www.physiology.org/doi/pdf/10.1152/ajplegacy.1960.198.5.1032

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