The Na+-K+-ATPase is needed in glia of touch receptors for responses to touch inC. elegans-Reference-Cited by-同舟云学术

The Na+-K+-ATPase is needed in glia of touch receptors for responses to touch inC. elegans

Published:2020-05-01 Issue:5 Volume:123 Page:2064-2074
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

Johnson Christina K.¹,Fernandez-Abascal Jesus¹,Wang Ying¹,Wang Lei¹,Bianchi Laura¹

Affiliation:

1. Department Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, Florida

Abstract

Increasing evidences support that accessory cells in mechanosensors regulate neuronal output; however, the glial molecular mechanisms that control this regulation are not fully understood. We show here in Caenorhabditis elegans that specific glial Na+-K+-ATPase genes are needed for nose touch-avoidance behavior. Our data support the requirement of these Na+-K+-ATPases for homeostasis of Na+and K+in nose touch receptors. Our data add to our understanding of glial regulation of mechanosensors.

Funder

NIH

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

Link

https://journals.physiology.org/doi/pdf/10.1152/jn.00636.2019

Reference56 articles.

1. The genetics of feeding in Caenorhabditis elegans.

2. Glia Are Essential for Sensory Organ Function in C. elegans

3. Mechanotransduction: Touch and Feel at the Molecular Level as Modeled in Caenorhabditis elegans

4. Leukoencephalopathy upon Disruption of the Chloride Channel ClC-2

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