Projections from the pelvic nerve to the periphery of the cat's thalamic ventral posterolateral nucleus and adjacent regions of the posterior complex

Abstract

1. Mapping experiments were performed in the region of the ventral posterolateral nucleus of the lateral thalamus in pentobarbitone-anesthetized cats with the aim to locate foci with input from the electrically stimulated pelvic nerve. The locations of the recording sites were verified in Nissl-stained histological sections with reference to electrolytic lesions. 2. Of the 68 visceroceptive thalamic neurons identified, 63% were located in the periphery of the ventral posterolateral nucleus (VPLp) and 34% in the dorsal, lateral, and medial aspects of the posterior complex (POd, POl, and POm, respectively) directly adjacent to VPLp. The region surrounding the middle and caudal part of the ventral posterolateral nucleus (VPL) received a much denser input from the pelvic nerve than that around the rostral pole of VPL. 3. The response latencies of the thalamic neurons to pelvic nerve stimulation ranged from 10 to 65 ms (median: 16 ms; interquartile distance: 12–20 ms) indicating a transmission of information from the pelvic space via small and large diameter myelinated fibers. 4. Seventy-nine percent of the visceroceptive neurons tested (n = 58), in addition, had low threshold somatic receptive fields that were located in 67% of the cases in regions of the lower back, the thigh, the tail and/or the heel and in 26% of the cases on the hindfoot. None of the 40 visceroceptive neurons tested with noxious mechanical stimulation of the skin responded to this kind of stimulus.(ABSTRACT TRUNCATED AT 250 WORDS)