In vitro chronic glycation induces AGEs accumulation reducing insulin-stimulated glucose uptake and increasing GLP1R in adipocytes-Reference-Cited by-同舟云学术

In vitro chronic glycation induces AGEs accumulation reducing insulin-stimulated glucose uptake and increasing GLP1R in adipocytes

Published:2021-05-01 Issue:5 Volume:320 Page:E976-E988
ISSN:0193-1849
Container-title:American Journal of Physiology-Endocrinology and Metabolism
language:en
Short-container-title:American Journal of Physiology-Endocrinology and Metabolism

Author:

Chilelli Nino-Cristiano¹,Faggian Alessia²,Favaretto Francesca²^ORCID,Milan Gabriella²,Compagnin Chiara²,Dassie Francesca²,Bettini Silvia²,Roverso Marco³,Seraglia Roberta⁴,Lapolla Annunziata¹,Vettor Roberto²

Affiliation:

1. Department of Medicine, University of Padua, Diabetology and Dietetics, Padua, Italy

2. Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy

3. Department of Chemical Sciences, University of Padua, Padua, Italy

4. Consiglio Nazionale delle Ricerche-Istituto di Chimica della Materia Condensata e di Tecnologie per l’Energia (CNR-ICMATE), Padua, Italy

Abstract

Intracellular AGEs accumulation increases RAGE and GLP1R and reduces glucose uptake in adipocytes.

Funder

MIUR

Diabetes Research Foundation

Publisher

American Physiological Society