Exercise training and spexin ameliorate thyroid changes in obese type 2 diabetic rats: the possible interlaying mechanisms-Reference-Cited by-同舟云学术

Exercise training and spexin ameliorate thyroid changes in obese type 2 diabetic rats: the possible interlaying mechanisms

Published:2024-09-01 Issue:3 Volume:327 Page:E313-E327
ISSN:0193-1849
Container-title:American Journal of Physiology-Endocrinology and Metabolism
language:en
Short-container-title:American Journal of Physiology-Endocrinology and Metabolism

Author:

Rizk Fatma H.¹,Barhoma Ramez A. E.¹²^ORCID,El-Saka Mervat H.¹,Ibrahim Hoda A.³,El-Gohary Rehab M.³,Ismail Radwa⁴,Motawea Shaimaa M.⁴,Salem Ola⁵,Hegab Islam Ibrahim¹⁶

Affiliation:

1. Department of Physiology, Faculty of Medicine, Tanta University, Tanta, Egypt

2. Department of Restorative Dentistry and Basic Medical Sciences, Faculty of Dentistry, University of Petra, Amman, Jordan

3. Department of Medical Biochemistry, Faculty of Medicine, Tanta University, Tanta, Egypt

4. Department of Anatomy and Embryology, Faculty of Medicine, Tanta University, Tanta, Egypt

5. Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta, Egypt

6. Department of Bio-Physiology, Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia

Abstract

This study proves, for the first time, the beneficial effects of SPX on thyroid dysfunction in obese diabetic rats and suggests that SPX mediates the EX effect on thyroid gland and exerts its effect mainly via GALR2.

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpendo.00213.2024

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