Resveratrol mediates the miR-149/HMGB1 axis and regulates the ferroptosis pathway to protect myocardium in endotoxemia mice

Author:

Wang Xiaoli1,Simayi Alimujiang1,Fu Juan1,Zhao Xuan1,Xu Guiping1ORCID

Affiliation:

1. Department of Anesthesiology, People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Clinical Research Center for Anesthesia Management, Ürümqi, People’s Republic of China

Abstract

Sepsis is an unusual systemic reaction. Resveratrol is involved in sepsis treatment. This study explored the mechanism of resveratrol on sepsis by regulating the miR-149/HMGB1 axis.

Funder

Foundation for Innovative Research Groups of the National Natural Science Foundation of China

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology,Endocrinology, Diabetes and Metabolism

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