The effects of a 6-month intervention aimed to reduce sedentary time on skeletal muscle insulin sensitivity: a randomized controlled trial-Reference-Cited by-同舟云学术

The effects of a 6-month intervention aimed to reduce sedentary time on skeletal muscle insulin sensitivity: a randomized controlled trial

Published:2023-08-01 Issue:2 Volume:325 Page:E152-E162
ISSN:0193-1849
Container-title:American Journal of Physiology-Endocrinology and Metabolism
language:en
Short-container-title:American Journal of Physiology-Endocrinology and Metabolism

Author:

Sjöros Tanja¹^ORCID,Laine Saara¹^ORCID,Garthwaite Taru¹^ORCID,Vähä-Ypyä Henri²^ORCID,Koivumäki Mikko¹,Eskola Olli¹,Löyttyniemi Eliisa³,Houttu Noora⁴,Laitinen Kirsi⁴^ORCID,Kalliokoski Kari K.¹^ORCID,Sievänen Harri²^ORCID,Vasankari Tommi²⁵,Knuuti Juhani¹,Heinonen Ilkka H. A.¹⁶^ORCID

Affiliation:

1. Turku PET Centre, University of Turku, Åbo Akademi University, and Turku University Hospital, Turku, Finland

2. The UKK Institute for Health Promotion Research, Tampere, Finland

3. Department of Biostatistics, University of Turku, Turku, Finland

4. Institute of Biomedicine, University of Turku, Turku, Finland

5. Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland

6. Rydberg Laboratory of Applied Sciences, University of Halmstad, Halmstad, Sweden

Abstract

Aiming to reduce daily SB by 1 h/day had no impact on skeletal muscle insulin sensitivity in the weight-bearing thigh muscles. However, successfully reducing SB may increase insulin sensitivity in the postural hamstring muscles. This emphasizes the importance of both reducing SB and increasing moderate-to-vigorous physical activity to improve insulin sensitivity in functionally different muscles of the body and thus induce a more comprehensive change in insulin sensitivity in the whole body.

Funder

Academy of Finland

Diabetestutkimussäätiö

Juho Vainion Säätiö

Suomen Kulttuurirahasto

Turun Yliopistollisen Keskussairaalan Koulutus- ja Tutkimussäätiö

Turun Yliopistosäätiö

Varsinais-Suomen Sairaanhoitopiiri

Yrjö Jahnssonin Säätiö

Publisher

American Physiological Society

Subject