PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2′-O-Me-cAMP-AM in human islets of Langerhans
Author:
Affiliation:
1. Departments of 1Medicine,
2. Pharmacology, and
3. Cell Biology, State University of New York, Upstate Medical University, Syracuse, New York; and
4. Biolog Life Science Institute, Bremen, Germany
Abstract
Publisher
American Physiological Society
Subject
Physiology (medical),Physiology,Endocrinology, Diabetes and Metabolism
Link
https://www.physiology.org/doi/pdf/10.1152/ajpendo.00630.2009
Reference72 articles.
1. Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters
2. Priming of insulin granules for exocytosis by granular Cl− uptake and acidification
3. Glucagon-Like Peptide 1 Elevates Cytosolic Calcium in Pancreaticβ -Cells Independently of Protein Kinase A1
4. Insulin Secretion
5. Epac proteins: multi-purpose cAMP targets
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