Frequency-dependent spike-pattern changes in motor cortex during thalamic deep brain stimulation-Reference-Cited by-同舟云学术

Frequency-dependent spike-pattern changes in motor cortex during thalamic deep brain stimulation

Published:2020-11-01 Issue:5 Volume:124 Page:1518-1529
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

Bello Edward M.¹^ORCID,Agnesi Filippo¹,Xiao Yizi¹,Dao Joan¹,Johnson Matthew D.¹²^ORCID

Affiliation:

1. Department of Biomedical Engineering, University of Minnesota, Minneapolis

2. Institute for Translational Neuroscience, University of Minnesota, Minneapolis

Abstract

The network mechanisms of thalamic deep brain stimulation (DBS) are not well understood at the cellular level. This study investigated the neuronal firing rate and pattern changes in the motor cortex resulting from stimulation of the cerebellar-receiving area of the motor thalamus. We showed that there is a nonintuitive relationship between general entropy-based spike-pattern measures and phase-locked regularization to DBS.

Funder

HHS | NIH | National Institute of Neurological Disorders and Stroke

HHS | NIH | National Institute of Mental Health

HHS | NIH | National Institute of Biomedical Imaging and Bioengineering

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

Link

https://journals.physiology.org/doi/pdf/10.1152/jn.00198.2020

Reference81 articles.

1. Synaptic Depression and Cortical Gain Control