Differential components of bradykinesia in Parkinson’s disease revealed by deep brain stimulation-Reference-Cited by-同舟云学术

Differential components of bradykinesia in Parkinson’s disease revealed by deep brain stimulation

Published:2024-09-01 Issue:3 Volume:132 Page:870-878
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

Mazzoni Pietro¹²^ORCID,Ushe Mwiza²,Younce John R.²^ORCID,Norris Scott A.²^ORCID,Hershey Tamara²,Karimi Morvarid²,Tabbal Samer D.²,Perlmutter Joel S.²^ORCID

Affiliation:

1. Division of Movement Disorders, Department of Neurology, The Ohio State University, Columbus, Ohio, United States

2. Division of Movement Disorders, Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, United States

Abstract

In this study, we examined different components of bradykinesia in patients with Parkinson’s disease (PD). We identified different components through signal processing techniques and their response to deep brain stimulation (DBS). We found that some components of bradykinesia respond to stimulation, whereas others do not. This knowledge advances our understanding of brain mechanisms that control movement speed and amplitude.

Funder

American Parkinson Disease Association

HHS | NIH | National Institute of Neurological Disorders and Stroke

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/jn.00320.2022

Reference35 articles.

1. Bradykinesia: Why do Parkinson's patients have it and what trouble does it cause?

2. The BRadykinesia Akinesia INcoordination (BRAIN) Tap Test: Capturing the Sequence Effect

3. What features improve the accuracy of clinical diagnosis in Parkinson's disease: A clinicopathologic study

4. The sequence effect and gait festination in Parkinson disease: Contributors to freezing of gait?

5. Characteristics of the sequence effect in Parkinson's disease