Contrast detection is enhanced by deterministic, high-frequency transcranial alternating current stimulation with triangle and sine waveform

Author:

Potok Weronika12ORCID,van der Groen Onno3ORCID,Sivachelvam Sahana1,Bächinger Marc12ORCID,Fröhlich Flavio45678ORCID,Kish Laszlo B.9ORCID,Wenderoth Nicole1210ORCID

Affiliation:

1. Neural Control of Movement Lab, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland

2. Neuroscience Center Zurich (ZNZ), Federal Institute of Technology Zurich, University and Balgrist Hospital Zurich, University of Zurich, Zurich, Switzerland

3. Neurorehabilitation and Robotics Laboratory, School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia

4. Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

5. Carolina Center for Neurostimulation, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

6. Department of Neurology, University of North Carolina at Chapel Hill, North Carolina, United States

7. Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, North Carolina, United States

8. Department of Biomedical Engineering, University of North Carolina at Chapel Hill, North Carolina, United States

9. Department of Electrical & Computer Engineering, Texas A&M University, College Station, Texas, United States

10. Future Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore

Abstract

Our findings extend our understanding of neuromodulation induced by noninvasive electrical stimulation. We provide the first evidence showing acute online benefits of transcranial alternating current stimulation (tACS)triangle and tACSsine targeting the primary visual cortex (V1) on visual contrast detection in accordance with the resonance-like phenomenon. The “deterministic” tACS and “stochastic” high-frequency-transcranial random noise stimulation (tRNS) are equally effective in enhancing visual contrast detection.

Funder

Swiss National Science Foundation

National Research Foundation Singapore

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

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