Safety and effects of a therapeutic 15 Hz rTMS protocol administered at different suprathreshold intensities in able-bodied individuals-Reference-Cited by-同舟云学术

Safety and effects of a therapeutic 15 Hz rTMS protocol administered at different suprathreshold intensities in able-bodied individuals

Published:2023-01-01 Issue:1 Volume:129 Page:56-65
ISSN:0022-3077
Container-title:Journal of Neurophysiology
language:en
Short-container-title:Journal of Neurophysiology

Author:

Brihmat Nabila¹²^ORCID,Allexandre Didier³²^ORCID,Bayram Mehmed B.¹,Saleh Soha³²,Guan Xiaofei⁴,Yue Guang H.³²,Zhong Jian⁴^ORCID,Forrest Gail F.¹³²^ORCID

Affiliation:

1. Tim and Caroline Reynolds Center for Spinal Stimulation, Kessler Foundation, West Orange, New Jersey

2. Department of Physical Medicine and Rehabilitation, Rutgers—New Jersey Medical School, Newark, New Jersey

3. Center for Mobility and Rehabilitation Engineering Research, Kessler Foundation, West Orange, New Jersey

4. Burke Neurological Institute and Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, White Plains, New York

Abstract

The results of this pilot study show the effects of a therapeutically promising 15 Hz repetitive transcranial magnetic stimulation (rTMS) protocol, administered at different suprathreshold intensities in able-bodied individuals. Although tolerable and feasible with a neuromodulatory potential, 15 Hz rTMS might result in persistent excitability that needs to be closely monitored if administered at suprathreshold stimulation intensity. These results reaffirm the importance of feasibility studies, especially in translational animal-to-human research.

Funder

Tim Reynolds Foundation

Council on Graduate Medical Education, New York State Department of Health

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

Link

https://journals.physiology.org/doi/pdf/10.1152/jn.00268.2022

Reference46 articles.

1. Induction of speech arrest and counting errors with rapid-rate transcranial magnetic stimulation

2. Safety of rapid-rate transcranial magnetic stimulation in normal volunteers

3. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014–2018)

4. Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines

5. A comprehensive review of the effects of rTMS on motor cortical excitability and inhibition