Initial and corrective submovement encoding differences within primary motor cortex during precision reaching

Author:

Schwartze Kevin C.12ORCID,Lee Wei-Hsien13ORCID,Rouse Adam G.1234ORCID

Affiliation:

1. Department of Neurosurgery, University of Kansas Medical Center, Kansas City, Kansas, United States

2. Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States

3. Bioengineering Program, University of Kansas, Lawrence, Kansas, United States

4. Department of Electrical Engineering and Computer Science, University of Kansas, Lawrence, Kansas, United States

Abstract

Neuronal recordings matched with kinematic behavior were collected in a precision center-out task that often required corrective movements. We reveal large differences in preferred direction and depth of modulation between initial and corrective submovements across the neural population. We then present a model of the neural population describing how these shifts in tuning create different subspaces for signaling initial and corrective movements likely to improve motor precision.

Funder

Frank and Evangeline Thompson Opportunity Fund

Steve Palermo Fund

HHS | NIH | National Institute of Neurological Disorders and Stroke

Publisher

American Physiological Society

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