Bariatric surgery decreases the capacity of plasma from obese asthmatic subjects to augment airway epithelial cell proinflammatory cytokine production-Reference-Cited by-同舟云学术

Bariatric surgery decreases the capacity of plasma from obese asthmatic subjects to augment airway epithelial cell proinflammatory cytokine production

Published:2024-01-01 Issue:1 Volume:326 Page:L71-L82
ISSN:1040-0605
Container-title:American Journal of Physiology-Lung Cellular and Molecular Physiology
language:en
Short-container-title:American Journal of Physiology-Lung Cellular and Molecular Physiology

Author:

Peña-García Paola E.¹²³^ORCID,Fastiggi V. Amanda¹²³,Mank Madeleine M.¹²,Ather Jennifer L.¹²^ORCID,Garrow Olivia J.¹²,Anathy Vikas¹⁴^ORCID,Dixon Anne E.¹²,Poynter Matthew E.¹²^ORCID

Affiliation:

1. Vermont Lung Center, University of Vermont, Burlington, Vermont, United States

2. Pulmonary Disease and Critical Care Medicine, University of Vermont, Burlington, Vermont, United States

3. Cellular, Molecular, and Biomedical Sciences doctoral program, University of Vermont, Burlington, Vermont, United States

4. Department of Pathology and Laboratory Medicine, University of Vermont, Burlington, Vermont, United States

Abstract

This longitudinal study following subjects with asthma and obesity reveals that weight loss following bariatric surgery decreases the capacity for plasma to augment proinflammatory cytokine secretion by human bronchial epithelial cells, implicating that circulating but not adipocyte-derived factors are important modulators in obese asthma.

Funder

HHS | National Institutes of Health

Publisher

American Physiological Society

Subject

Cell Biology,Physiology (medical),Pulmonary and Respiratory Medicine,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajplung.00205.2023

Reference37 articles.

1. Asthma

2. Mechanisms of Asthma in Obesity. Pleiotropic Aspects of Obesity Produce Distinct Asthma Phenotypes

3. Obesity and severe asthma

4. Obesity and asthma

5. The effect of obesity on lung function

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