Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesia-Reference-Cited by-同舟云学术

Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesia

Published:2024-04-01 Issue:4 Volume:326 Page:L468-L476
ISSN:1040-0605
Container-title:American Journal of Physiology-Lung Cellular and Molecular Physiology
language:en
Short-container-title:American Journal of Physiology-Lung Cellular and Molecular Physiology

Author:

Gaston Benjamin¹,Smith Laura A.¹^ORCID,Davis Michael D.¹,Saunders Jessica¹,Daniels Ivana¹,Horani Amjad²^ORCID,Brody Steven L.²,Giddings Olivia³,Zhao Yi⁴,Marozkina Nadzeya¹^ORCID

Affiliation:

1. Herman B. Wells Center for Pediatric Research, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, United States

2. Department of Medicine, Washington University, St. Louis, Missouri, United States

3. Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States

4. Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana, United States

Abstract

The PCD airway epithelium does not optimally clear antigens, and antigen exposure can lead to NO oxidation and nitrosative stress. Oxidation caused by antigen stasis could represent a therapeutic target in PCD, and there are convenient monitoring biomarkers.

Funder

Foundation for the National Institutes of Health

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/ajplung.00208.2022

Reference45 articles.

1. Primary ciliary dyskinesia (PCD): A genetic disorder of motile cilia

2. The global prevalence and ethnic heterogeneity of primary ciliary dyskinesia gene variants: a genetic database analysis

3. Diagnosis, monitoring, and treatment of primary ciliary dyskinesia: PCD foundation consensus recommendations based on state of the art review

4. Primary Ciliary Dyskinesia

5. Upper and lower airway nitric oxide levels in primary ciliary dyskinesia, cystic fibrosis and asthma

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Primary Ciliary Dyskinesia;Pediatrics;2024-05-02