New insights into the natural history of bronchopulmonary dysplasia from proteomics and multiplexed immunohistochemistry

Author:

Dylag Andrew M.1ORCID,Misra Ravi S.1ORCID,Bandyopadhyay Gautam1ORCID,Poole Cory1ORCID,Huyck Heidie L.1ORCID,Jehrio Matthew G.1,Haak Jeannie1,Deutsch Gail H.2ORCID,Dvorak Carly1,Olson Heather M.3ORCID,Paurus Vanessa3,Katzman Philip J.4,Woo Jongmin3ORCID,Purkerson Jeffrey M.1ORCID,Adkins Joshua N.3ORCID,Mariani Thomas J.1ORCID,Clair Geremy C.3ORCID,Pryhuber Gloria S.1ORCID

Affiliation:

1. Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, United States

2. Department of Laboratory Medicine and Pathology, University of Washington, University of Washington, Seattle, Washington, United States

3. Pacific Northwest National Laboratories, Richland, Washington, United States

4. Department of Pathology, University of Rochester Medical Center, Rochester, New York, United States

Abstract

We provide new insights into the natural history of bronchopulmonary dysplasia in donor human lungs after the neonatal intensive care unit hospitalization. This study provides new insights into how the proteome and histopathology of BPD changes in early childhood, uncovering novel pathways for future study.

Funder

DOE | NNSA | LDRD | PNNL | Environmental Molecular Sciences Laboratory

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Physiological Society

Subject

Cell Biology,Physiology (medical),Pulmonary and Respiratory Medicine,Physiology

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Research Accomplishments in Pulmonary, Critical Care, and Sleep: A Retrospective Review;American Journal of Respiratory and Critical Care Medicine;2023-12-15

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