Affiliation:
1. Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Rehabilitation Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China
2. Zhongshan Medical School, Guangdong Province Key Laboratory of Brain Function and Disease, Sun Yat-Sen University, Guangzhou, China
Abstract
Our study demonstrates that methylglyoxal accumulation via increasing advanced glycation end-product levels in dorsal root ganglion contributes to the persistent pain induced by lumbar disk herniation, which proposed potential targets for the treatment of lumbar disk herniation-induced persistent pain.
Funder
National Natural Science Foundation of China (NSFC)
Natural Science Foundation of Guangdong Province
Guangzhou Science and Technology Plan Projects
Key Laboratory of Malignant Tumor Gene Regulation and Target Therapy of Guangdong Higher Education Institutes
China Postdoctoral Science Foundation
Key Laboratory of Maliganant Tumor Molecular Mechanism and Translational Medicine of Guangzhou Bureau of Science and Information Technology
Foundamental Research Funds for the Central Universities
Publisher
American Physiological Society
Subject
Physiology,General Neuroscience
Cited by
20 articles.
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