Corticospinal excitability across lower limb muscles in humans

Author:

Eisner-Janowicz Ines1,Chen Bing123ORCID,Sangari Sina12ORCID,Perez Monica A.1423ORCID

Affiliation:

1. Shirley Ryan AbilityLab, Chicago, Illinois, United States

2. Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, Illinois, United States

3. Edward Hines Jr. VA Hospital, Hines, Illinois, United States

4. Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, Illinois, United States

Abstract

We provide evidence on how corticospinal output differs across muscles in the leg in intact humans. We found that corticospinal responses were larger in a distal intrinsic foot muscle and were smaller in the biceps femoris compared to all other muscles in the leg. Increases in corticospinal excitability to an intrinsic foot muscle could have a spinal origin.

Funder

U.S. Department of Veterans Affairs

Craig H. Neilsen Foundation

HHS | NIH | National Institute of Neurological Disorders and Stroke

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

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