Motor cortical thickness is related to effort-based decision-making in humans

Author:

Umesh Amith1,Kutten Kwame S.23,Hogan Patrick S.3,Ratnanather J. Tilak23ORCID,Chib Vikram S.34

Affiliation:

1. Department of Biophysics, Johns Hopkins University, Baltimore, Maryland

2. Center for Imaging Science and Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland

3. Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, Maryland

4. Kennedy Krieger Institute, Baltimore, Maryland

Abstract

How effortful a task feels is an integral aspect of human decision-making that influences choices to engage in physical activity. We show that properties of motor cortex (the brain region responsible for physical exertion) are related to assessments of effort and decisions to exert. These findings provide a link between the anatomical properties of motor cortex and the cognitive function of effort-based choice.

Funder

HHS | NIH | National Institute of Child Health and Human Development

HHS | NIH | NICHD | National Center for Medical Rehabilitation Research

HHS | NIH | National Institute of Mental Health

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Physiological Society

Subject

Physiology,General Neuroscience

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