Affiliation:
1. Department of Biology, Miami University, Oxford, Ohio
Abstract
Feedback from central pattern generator (CPG) circuits patterns activity of their projection neuron inputs. However, whether the intraburst firing rate between rhythmic feedback inhibition is also impacted by CPG feedback was not known. I establish that CPG feedback can alter the projection neuron intraburst firing rate through interactions with projection neuron intrinsic properties. The contribution of feedback to projection neuron activity level is specific to the modulatory condition, demonstrating a state dependence for this novel role of circuit feedback.
Funder
National Science Foundation (NSF)
Publisher
American Physiological Society
Subject
Physiology,General Neuroscience
Cited by
16 articles.
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