Consensus draft of the native mouse podocyte-ome

Author:

Hutzfeldt Arvid D.1ORCID,Tan Yifan2ORCID,Bonin Léna Lydie2ORCID,Beck Bodo B.3,Baumbach Jan4,Lassé Moritz1ORCID,Demir Fatih2ORCID,Rinschen Markus M.125ORCID

Affiliation:

1. III Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

2. Department of Biomedicine, Aarhus University, Aarhus, Denmark

3. Institute of Human Genetics, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

4. Institute for Computational Systems Biology, University of Hamburg, Hamburg, Germany

5. Aarhus Institute of Advanced Studies, Aarhus University, Aarhus, Denmark

Abstract

Podocytes are key components of glomerular filtration and are affected in various kidney diseases. Here, we present an integrated, robust definition of molecular identity across proteomic, single-cell transcriptomics, and bulk transcriptomic studies on native mouse podocytes. We created the “PodIdent” app, a novel knowledge base promoting access to the presence and expression of specific proteins for podocytes.

Publisher

American Physiological Society

Subject

Physiology

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Perspective on G protein-coupled receptors in renal physiology;American Journal of Physiology-Renal Physiology;2023-12-01

2. Role of TFEB in regulation of the podocyte actin cytoskeleton;Archives of Biochemistry and Biophysics;2023-10

3. An integrated organoid omics map extends modeling potential of kidney disease;Nature Communications;2023-08-14

4. The PRIDE database resources in 2023;Nephrology Dialysis Transplantation;2023-08-11

5. Call for Papers: podocyte physiology and pathophysiology;American Journal of Physiology-Renal Physiology;2023-05-01

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