High dietary salt intake increases urinary NGAL excretion and creatinine clearance in healthy young adults

Author:

Barnett Alex M.1,Babcock Matthew C.23ORCID,Watso Joseph C.24ORCID,Migdal Kamila U.25,Gutiérrez Orlando M.6,Farquhar William B.2,Robinson Austin T.1ORCID

Affiliation:

1. Neurovascular Physiology Laboratory, School of Kinesiology, Auburn University, Auburn, Alabama

2. Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware

3. Division of Geriatric Medicine, University of Colorado-Anschutz Medical Campus, Aurora, Colorado

4. Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas

5. War Related Illness and Injury Study Center, Washington DC Department of Veteran Affairs Medical Center, Washington, District of Columbia

6. Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama

Abstract

In healthy young adults, 10 days of dietary salt loading increased creatinine clearance and increased urinary excretion of the kidney injury biomarker marker neutrophil gelatinase-associated lipocalin despite no change in resting blood pressure.

Funder

American College of Sports Medicine

American Heart Association

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Physiological Society

Subject

Physiology

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