The apical 70-pS K+ channel in the thick ascending limb of Henle’s loop is a large-conductance Na+-and Cl–-activated, KNa1.1-like, channel

Abstract

This study highlights new regulatory and conductive properties of the as yet poorly molecularly defined 70-pS K+ channel in the apical membrane of the thick ascending limb of Henle’s loop cells of the mouse kidney that functionally identify it as a large-conductance, Na+- and Cl–-activated KNa1.1-like channel.