Angiotensin II acts through Rac1 to upregulate pendrin: role of NADPH oxidase-Reference-Cited by-同舟云学术

Angiotensin II acts through Rac1 to upregulate pendrin: role of NADPH oxidase

Published:2024-02-01 Issue:2 Volume:326 Page:F202-F218
ISSN:1931-857X
Container-title:American Journal of Physiology-Renal Physiology
language:en
Short-container-title:American Journal of Physiology-Renal Physiology

Author:

Pham Truyen D.¹,Verlander Jill W.²,Chen Chao²,Pech Vladimir¹,Kim Hailey I.¹,Kim Young Hee¹,Weiner I. David²³^ORCID,Milne Ginger L.⁴^ORCID,Zent Roy⁵⁶^ORCID,Bock Fabian⁵⁶,Brown Dennis⁷^ORCID,Eaton Amity⁷^ORCID,Wall Susan M.¹^ORCID

Affiliation:

1. Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States

2. Division of Nephrology, Hypertension and Renal Transplantation, The University of Florida College of Medicine, Gainesville, Florida, United States

3. Nephrology and Hypertension Section, Gainesville Veterans Affairs Medical Center, Gainesville, Florida, United States

4. Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, United States

5. Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States

6. Department of Veterans Affairs Hospital, Nashville, Tennessee, United States

7. Program in Membrane Biology, Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States

Abstract

This study defines a new signaling mechanism by which angiotensin II modulates oxidative stress and blood pressure.

Funder

HHS | NIH | NCI | Basic Research Laboratory

HHS | NIH | NIH Office of the Director

HHS | NIH | National Eye Institute

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Veterans Administration Medical Center

Publisher

American Physiological Society

Subject

Physiology