1. Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada;
2. Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada;
3. Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada;
4. Division of Cardiology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; and
5. Division of Nephrology, Department of Medicine, University of Toronto, Ontario, Canada
6. Department of Physiology, University of Alberta, Edmonton, Alberta, Canada;