Does COVID-19 impair V̇o2peak in patients with cardiorespiratory disease? Insight from cardiopulmonary responses to maximal exercise pre- and post-illness

Author:

Fernandes Igor A.12ORCID,Balavenkataraman Arvind3,Bonvie-Hill Natalie E.1,Patel Neal M.3,Taylor Bryan J.1,Helgeson Scott A.3ORCID

Affiliation:

1. Cardiovascular Disease, Mayo Clinic, Jacksonville, Florida, United States

2. Department of Health and Kinesiology, Purdue University, West Lafayette, Indiana, United States

3. Pulmonary & Critical Care Medicine, Mayo Clinic, Jacksonville, Florida, United States

Abstract

There is accumulating evidence that reduced exercise capacity is, or can be, an outcome following COVID-19. However, evidence to date relies upon cross-sectional approaches that either do not consider patients with concomitant cardiorespiratory disease or account for pre-infection exercise capacity data. Accounting for V̇o2peak before COVID-19 and including a group of control patients, we find limited evidence for reduced exercise capacity as a sequela of SARS-CoV-2 infection in patients with concomitant cardiorespiratory disease.

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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