Predicting tracheal work of breathing in neonates based on radiological and pulmonary measurements

Author:

Gunatilaka Chamindu C.12ORCID,Hysinger Erik B.23,Schuh Andreas4,Xiao Qiwei12,Gandhi Deep B.15,Higano Nara S.1235,Ignatiuk Daniel12ORCID,Hossain Md M.36,Fleck Robert J.5,Woods Jason C.1235,Bates Alister J.12357ORCID

Affiliation:

1. Center for Pulmonary Imaging Research, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio

2. Division of Pulmonary Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio

3. Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio

4. Department of Computing, Imperial College London, London, United Kingdom

5. Department of Radiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio

6. Division of Biostatistics and Epidemiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio

7. Department of Biomedical Engineering, University of Cincinnati, Cincinnati, Ohio

Abstract

The work of breathing due to resistance in the trachea is an important metric for quantifying the effect of tracheal abnormalities such as tracheomalacia, but currently requires complex dynamic imaging and computational fluid dynamics simulation to calculate it. This study produces a method to predict the tracheal work of breathing based on readily available imaging and clinical metrics.

Funder

Cincinnati Children's Hospital Medical Center

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Tracheomalacia Reduces Aerosolized Drug Delivery to the Lung;Journal of Aerosol Medicine and Pulmonary Drug Delivery;2023-12-08

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