Sex-specific maturation of muscle metabolites carnosine, creatine, and carnitine over puberty: a longitudinal follow-up study

Author:

Lievens Eline1ORCID,Van Vossel Kim1,Van de Casteele Freek1,Baguet Audrey1,Derave Wim1ORCID

Affiliation:

1. Department of Movement and Sports Sciences, Ghent University, Ghent, Belgium

Abstract

This is the first study to investigate sexual dimorphisms in skeletal muscle carnosine, creatine, and carnitine concentrations in a substantial adult reference population ( n = 100). A sexual dimorphism is present in both carnosine and creatine at adult age. The origin of the sexual dimorphisms is investigated using a longitudinal design over puberty in 24 males and 24 females. The sexual dimorphism in carnosine originated partly during puberty for carnosine, but not for creatine.

Funder

Fonds Wetenschappelijk Onderzoek

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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