Severity of central sleep apnea does not affect sleeping oxygen saturation during ascent to high altitude

Author:

Bird Jordan D.1,Kalker Anne12,Rimke Alexander N.1,Chan Jason S.1,Chan Garrick1,Saran Gurkarn1,Jendzjowsky Nicholas G.3,Wilson Richard J. A.4,Brutsaert Thomas D.5,Sherpa Mingma T.6,Day Trevor A.1ORCID

Affiliation:

1. Faculty of Science and Technology, Department of Biology, Mount Royal University, Calgary, Alberta, Canada

2. Radboud University Medical Center, Nijmegen, The Netherlands

3. Respiratory Medicine and Exercise Physiology, The Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, West Carson, California

4. Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children’s Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

5. Department of Exercise Science, School of Education, Syracuse University, Syracuse, New York

6. Kunde Hospital, Khunde, Nepal

Abstract

Central sleep apnea (CSA) is universal during ascent to high altitude, with intermittent and transient fluctuations in oxygen saturation, but the consequences on mean sleeping blood oxygenation are unclear. We assessed indices of CSA and mean sleeping peripheral oxygen saturation ([Formula: see text]) during ascent to high altitude using two ascent profiles: rapid ascent and residence at 3,800 m and incremental ascent to 5,160 m. The severity of CSA was not correlated with mean sleeping [Formula: see text] with ascent.

Funder

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Alberta Government

Alberta Innovates Health Solutions

University of Calgary

Francis Family Foundation

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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