CPAP combined with oral appliance therapy reduces CPAP requirements and pharyngeal pressure swings in obstructive sleep apnea

Author:

Tong Benjamin K.12ORCID,Tran Carolin3,Ricciardiello Andrea1,Donegan Michelle1,Chiang Alan K. I.1ORCID,Szollosi Irene4,Amatoury Jason5,Carberry Jayne C.123,Eckert Danny J.123ORCID

Affiliation:

1. Neuroscience Research Australia (NeuRA), Sydney, Australia

2. School of Medical Sciences, University of New South Wales, Sydney, Australia

3. Adelaide Institute for Sleep Health (AISH) and Flinders Health and Medical Research Institute (FHMRI), Flinders University, Adelaide, Australia

4. The Prince Charles Hospital, Brisbane, Australia

5. Biomedical Engineering Program, Maroun Semaan Faculty of Engineering and Architecture, American University of Beirut, Beirut, Lebanon

Abstract

Combined CPAP and oral appliance therapy has been suggested as an alternative for incomplete responders to oral appliance therapy. We used a novel oral appliance incorporating an oral airway together with CPAP to show that pharyngeal pressure swings were normalized at reduced CPAP levels. Our findings demonstrate that using CPAP and oral appliance together may be a beneficial alternative for incomplete responders to oral appliance therapy and intolerant CPAP users due to high-pressure requirements.

Funder

Cooperative Research Centre Project Grant, Australian Gov.

Department of Health, Australian Government | National Health and Medical Research Council

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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