Supraspinatus muscle architecture and physiology in a rabbit model of tenotomy and repair

Author:

Hyman Sydnee A.12,Wu Isabella T.2,Vasquez-Bolanos Laura S.12,Norman Mackenzie B.23,Esparza Mary C.2,Bremner Shannon N.2,Dorn Shanelle N.2,Ramirez Ivan2,Fithian Donald C.2,Lane John G.2,Singh Anshuman24,Ward Samuel R.125ORCID

Affiliation:

1. Department of Bioengineering, University of California, San Diego, California

2. Department of Orthopaedic Surgery, University of California, San Diego, California

3. Dartmouth Geisel School of Medicine, Hanover, New Hampshire

4. Department of Orthopaedic Surgery, Kaiser Permanente, San Diego, California

5. Department of Radiology, University of California, San Diego, California

Abstract

We utilize an established method to measure the length-tension relationship for the rabbit supraspinatus in normal, torn, and repaired muscles. We then perform architectural analysis to evaluate structural changes after tear and repair. Although peak isometric force is lower in the tear and repair groups, there are no differences in peak stresses across groups. These findings indicate persistent structural changes (both radial and longitudinal atrophy) and physiological deficiencies (decreased peak force and uncoupling structure-function relationship) after tenotomy that do not significantly recover after repair.

Funder

HHS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Large animal models for the study of tendinopathy;Frontiers in Cell and Developmental Biology;2022-10-25

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