Muscle-derived microRNAs correlated with thigh lean mass gains during progressive resistance training in older adults-Reference-Cited by-同舟云学术

Muscle-derived microRNAs correlated with thigh lean mass gains during progressive resistance training in older adults

Published:2024-08-01 Issue:2 Volume:137 Page:262-273
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

O’Bryan Samia M.¹²^ORCID,Lavin Kaleen M.³^ORCID,Graham Zachary A.³,Drummer Devin J.¹²^ORCID,Tuggle S. Craig³,Van Keuren-Jensen Kendall⁴,Reiman Rebecca⁴,Alsop Eric⁴,Kadakia Madhavi P.⁵,Craig Michael P.⁵,Zhang Jin⁵,Bamman Marcas M.¹²³^ORCID

Affiliation:

1. UAB Center for Exercise Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, United States

2. Department of Cell, Developmental, and Integrative Biology, The University of Alabama at Birmingham, Birmingham, Alabama, United States

3. Healthspan, Resilience, and Performance Research, Florida Institute for Human and Machine Cognition, Pensacola, Florida, United States

4. Translational Genomics Research Institute, Phoenix, Arizona, United States

5. Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States

Abstract

In this work, we identified a set of microRNAs correlated with thigh lean mass gains in a group of older adults. To our knowledge, this is the first time these microRNAs have been identified as novel predictive biomarkers correlating with lean mass gains in aging adults. As biomarkers, these may help interventionalists identify older individuals that are positively responding to an exercise intervention.

Funder

HHS | National Institutes of Health

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00680.2023

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