Measuring short-term changes in specific ventilation using dynamic specific ventilation imaging

Abstract

Dynamic imaging providing maps of specific ventilation with a temporal resolution of ∼7 min with a spatial resolution of ∼1 cm3 using MRI was shown to be practical. The technique provides an ionizing radiation-free means of temporally following the spatial pattern of specific ventilation. Reanalysis of previously published data showed that the effects of inhaled methacholine and albuterol were largely complete at ∼22 min and ∼9 min, respectively after administration.