Quadriceps fatigue during hypoxic and ischemic knee-extension exercise is similar in males and females

Author:

Dominelli Paolo B.12ORCID,Senefeld Jonathon W.23ORCID,Wiggins Chad C.24ORCID,Baker Sarah E.2ORCID,Clayburn Andrew J.2ORCID,Joyner Michael J.2ORCID

Affiliation:

1. Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Ontario, Canada

2. Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States

3. Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States

4. Department of Kinesiology, Michigan State University, East Lansing, Michigan, United States

Abstract

Hypoxia exacerbates fatigue via central mechanisms after ischemic single-leg exercise. The greater fatigue observed during ischemic dynamic fatiguing exercise with hypoxia inspirate did not differ between the sexes. Hypoxia-induced central limitations are present in acute ischemic exercise and do not appear different in males and females.

Funder

HHS | NIH | National Heart, Lung, and Blood Institute

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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