Cardiac remodeling in well-healed burn survivors after 6 months of unsupervised progressive exercise training

Author:

McKenna Zachary J.12ORCID,Moralez Gilbert3ORCID,Romero Steven A.4ORCID,Hieda Michinari5,Huang Mu6,Cramer Matthew N.12,Sarma Satyam12,MacNamara James P.12ORCID,Jaffery Manall F.12,Atkins Whitley C.12ORCID,Foster Josh12ORCID,Crandall Craig G.12ORCID

Affiliation:

1. Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas

2. Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas

3. Department of Applied Clinical Research, School of Health Professions, University of Texas Southwestern Medical Center, Dallas, Texas

4. Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas

5. Kyushu University, School of Medicine, Fukuoka, Japan

6. Office of Science, Medicine, and Health, American Heart Association, Dallas, Texas

Abstract

Aerobic exercise is important in the rehabilitation of individuals with prior burn injuries, but no studies have examined whether adult burn survivors demonstrate cardiac remodeling to long-term aerobic exercise training. In this study, we tested the hypothesis that 6 months of progressive exercise training would improve cardiac magnetic resonance imaging-based measures of cardiac structure and function in well-healed burn survivors. Our findings highlight the ability of exercise training to modify cardiac structure and function in well-healed burn survivors and nonburned sedentary controls alike.

Funder

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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