Critical closing pressure of the pharyngeal airway during routine drug-induced sleep endoscopy: feasibility and protocol

Author:

Kazemeini Elahe12ORCID,Van de Perck Eli12,Dieltjens Marijke12,Willemen Marc3,Verbraecken Johan45,Sands Scott A.6,Vanderveken Olivier M.23,Op de Beeck Sara123ORCID

Affiliation:

1. Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium

2. ENT, Head and Neck Surgery, Antwerp University Hospital, Edegem, Belgium

3. Multidisciplinary Sleep Disorders Centre, Antwerp University Hospital, Edegem, Belgium

4. Laboratory of Experimental Medicine and Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium

5. Department of Pulmonology, Antwerp University Hospital, Edegem, Belgium

6. Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts

Abstract

The protocol of this study was successful in concomitant measurement of Pcrit during routine clinical endoscopy. Comparison of two calculation methods for Pcrit showed that the inspiratory ventilation method is more successful in assessment of Pcrit in subjects with epiglottic collapse, associated with high negative effort dependence. Subjects with palatal complete concentric collapse during DISE had a wide Pcrit range suggesting no close correlation between Pcrit and this collapse pattern.

Funder

American Academy of Sleep Medicine (AASM) Foundation

Fonds Wetenschappelijk Onderzoek

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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