Intermittent compression induces transitory hypoxic stimuli, upstream vasodilation and enhanced perfusion of skin capillaries, independent of age and diabetes-Reference-Cited by-同舟云学术

Intermittent compression induces transitory hypoxic stimuli, upstream vasodilation and enhanced perfusion of skin capillaries, independent of age and diabetes

Published:2021-04-01 Issue:4 Volume:130 Page:1072-1084
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Thorn Clare E.¹^ORCID,Adio Aminat O.¹,Fox Roger H.¹,Gardner A. Michael¹,Winlove C. Peter¹,Shore Angela C.¹

Affiliation:

1. Diabetes and Vascular Medicine, Institute of Biomedical and Clinical Sciences, University of Exeter Medical School, College of Medicine and Health and NIHR Exeter Clinical Research Facility, and School of Physics and Astronomy, University of Exeter, Exeter, United Kingdom

Abstract

This study demonstrates that hand intermittent pneumatic compression evokes transitory hypoxic stimuli in distal finger skin microcirculation inducing vasodilation of arterial inflow vessels, enhanced perfusion, and maximum capillary recruitment in young and older subjects and older subjects with type 2 diabetes mellitus. Enhanced shear stress in the microcirculation did not appear to induce local skin vasodilation.

Funder

NIHR Exeter Clinical Research Facility

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00657.2020

Reference67 articles.

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