Altered accumulation of hepatic mitochondrial antioxidant proteins with age and environmental heat stress-Reference-Cited by-同舟云学术

Altered accumulation of hepatic mitochondrial antioxidant proteins with age and environmental heat stress

Published:2023-12-01 Issue:6 Volume:135 Page:1339-1347
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Haak Jodie L.¹,Kregel Kevin C.²,Bloomer Steven A.³^ORCID

Affiliation:

1. Health Sciences Department, Drexel University, Philadelphia, Pennsylvania, United States

2. Department of Health and Human Physiology, The University of Iowa, Iowa City, Iowa, United States

3. Division of Science and Engineering, Penn State Abington, Abington, Pennsylvania, United States

Abstract

Our results suggest heat stress-induced mitochondrial translocation of Sirt-3, MnSOD, and Ref-1 in young and old animals. Aged rats experienced a decline in Trx-2 after heat stress, suggesting a potential mechanism for age-related mitochondrial dysfunction.

Funder

Penn State Abington

HHS | NIH | Office of Extramural Research, National Institutes of Health

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00610.2023

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