The V̇e/V̇co2 slope: a useful tool to evaluate the physiological status of children with congenital heart disease

Author:

Gavotto Arthur12ORCID,Huguet Helena34,Picot Marie-Christine34,Guillaumont Sophie15,Matecki Stefan26,Amedro Pascal1246

Affiliation:

1. Paediatric and Congenital Cardiology Department, M3C Regional Reference CHD Centre, University Hospital of Montpellier, Montpellier, France

2. PhyMedExp, CNRS, INSERM, University of Montpellier, Montpellier, France

3. Epidemiology and Clinical Research Department, University Hospital of Montpellier, Montpellier, France

4. Clinical Investigation Centre, INSERM, University of Montpellier, Montpellier, France

5. Paediatric Cardiology and Rehabilitation Unit, St-Pierre Institute, Palavas-Les-Flots, France

6. Paediatric Functional Exploration Laboratory, Physiology Department, University Hospital of University of Montpellier, Montpellier, France

Abstract

Using V̇e/V̇co2 slope is useful for children with congenital heart disease. V̇e/V̇co2 slope is sensitive to pulmonary blood flow maldistribution during exercise, this concerns congenital heart disease with pulmonary regurgitation, tricuspid regurgitation, right ventricular hypertension, and right ventricle outflow tract obstacle. V̇e/V̇co2 slope is a good parameter to follow single ventricles and right heart residual lesions (tetralogy of Fallot; pulmonary atresia; truncus arteriosus…).

Funder

Montpellier University Hospital Clinical Research Program

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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