Sustained contractile force regulated by rho-kinase and protein kinase C in sheep carotid arterial smooth muscle-Reference-Cited by-同舟云学术

Sustained contractile force regulated by rho-kinase and protein kinase C in sheep carotid arterial smooth muscle

Published:2023-01-01 Issue:1 Volume:134 Page:152-159
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Smit Leanne C. M.¹²,Wang Lu¹,Chitano Pasquale¹,Seow Chun Y.¹³^ORCID

Affiliation:

1. UBC Centre for Heart Lung Innovation, University of British Columbia, Vancouver, Canada

2. Graduate School of Life Sciences, Utrecht University, Utrecht, The Netherlands

3. Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada

Abstract

The study supports a model that the maintenance of sustained force during a contraction of arterial smooth muscle is dependent on the intracellular transmission of force through the cytoskeleton and that ρ-kinase and protein kinase C plays an important role in the regulation of cytoskeletal integrity and its efficiency in force transmission.

Funder

Gouvernement du Canada | Canadian Institutes of Health Research

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00592.2022

Reference22 articles.

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2. Phosphorylation and Dephosphorylation of a Light Chain of the Chicken Gizzard Myosin Molecule12

3. Myosin Phosphorylation and the Cross-Bridge Cycle in Arterial Smooth Muscle

4. Cross-bridge phosphorylation and regulation of latch state in smooth muscle

5. The Small GTPase RhoA Regulates the Contraction of Smooth Muscle Tissues by Catalyzing the Assembly of Cytoskeletal Signaling Complexes at Membrane Adhesion Sites

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