The acute effects of exercise intensity and inorganic nitrate supplementation on vascular health in females after menopause

Author:

Hogwood Austin C.1ORCID,Ortiz de Zevallos Joaquin1ORCID,Weeldreyer Nathan1,Clark James R.1,Mazzella Vincent1,Cain Lauren1,Myaing Dylan1,Love Kaitlin M.2,Weltman Arthur13,Allen Jason D.13ORCID

Affiliation:

1. Department of Kinesiology, School of Education and Human Development, University of Virginia, Charlottesville, Virginia, United States

2. Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia, United States

3. Division of Cardiovascular Medicine, School of Medicine, University of Virginia, Charlottesville, Virginia, United States

Abstract

This study compared exercise-induced changes in flow-mediated dilation after acute moderate- and high-intensity exercise in females postmenopause supplementing either inorganic nitrate (beetroot juice) or placebo. BRJ improved peak ΔFMD postexercise, and BRJ + HIE increased FMD measured as FMD over time. Neither PL + MIE nor PL + HIE improved FMD. These findings suggest that inorganic nitrate supplementation combined with high-intensity exercise may benefit vascular health in females PM.

Funder

Foundation for the National Institutes of Health

UV | Curry School of Education and Human Development, University of Virginia

University of Virginia

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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