Chemoradiation to the submental muscles alters hyoid movement during swallowing in a rat model-Reference-Cited by-同舟云学术

Chemoradiation to the submental muscles alters hyoid movement during swallowing in a rat model

Published:2024-05-01 Issue:5 Volume:136 Page:1076-1086
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

King Suzanne N.¹^ORCID,Kuntz Abigail¹,Scott Nathan¹,Smiley Brittany¹,Portocarrero Bonifaz Andres²,Blackburn Megan²

Affiliation:

1. Department of Otolaryngology – Head and Neck Surgery and Communicative Disorders, School of Medicine, University of Louisville, Louisville, Kentucky, United States

2. Department of Radiation Oncology, School of Medicine, University of Louisville, Louisville, Kentucky, United States

Abstract

Chemoradiation treatment for head and neck cancer can cause functional impairments in swallowing, which can adversely affect quality of life. This study provides new evidence that chemoradiation targeted to the submental muscles provokes early adaptations in hyoid movement during swallowing, which correlate with changes in bolus size. We also demonstrate a method for tracking the hyoid during swallowing in a rat model of chemoradiation injury.

Funder

The AR-Hale Family Foundation

HHS | NIH | National Cancer Institute

Publisher

American Physiological Society

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00538.2023

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