Timing of acute passive heating on glucose tolerance and blood pressure in people with type 2 diabetes: a randomized, balanced crossover, control trial

Author:

James Thomas J.12ORCID,Corbett Jo1,Cummings Michael2,Allard Sharon2,Young John S.3ORCID,Towse Jonathan3,Carey-Jones Kathryn45,Eglin Clare1,Hopkins Billy1,Morgan Connor1,Tipton Michael1ORCID,Saynor Zoe L.12,Shepherd Anthony I.12ORCID

Affiliation:

1. School of Sport, Health and Exercise Science, Faculty of Science and Health, University of Portsmouth, United Kingdom

2. Diabetes and Endocrinology Department, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom

3. School of Pharmacy and Biomedical Sciences, Faculty of Science and Health, University of Portsmouth, United Kingdom

4. School of Biological Sciences, Faculty of Science and Health, University of Portsmouth, United Kingdom

5. Oaks Healthcare, Cowplain Family Practice, Waterlooville, United Kingdom

Abstract

This is the first study to investigate the timing of acute passive heating on glucose tolerance and extracellular heat shock protein 70 concentration ([eHSP70]) in people with type 2 diabetes. The principal novel findings from this study were that both passive heating conditions: 1) did not reduce the area under the curve or peak blood glucose concentration, 2) elevated heart rate, and 3) increased [eHSP70], which was blunted by glucose ingestion, while passive heating following glucose ingestion, 4) increased total energy expenditure, and 5) reduced diastolic blood pressure.

Funder

University of Portsmouth

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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